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from those which surrounded my generation in the seventies of the last century, when Virchow and his great contemporaries laid the sure and deep foundations of modern pathology. Which of you now knows the "Cellular Pathology" as we did? To many of you it is a closed book,--to many more Virchow may be thought a spent force. But no, he has only taken his place in a great galaxy. We do not forget the magnitude of his labors, but a new generation has new problems--his message was not for you--but that medicine today runs in larger moulds and turns out finer castings is due to his life and work. It is one of the values of lectures on the history of medicine to keep alive the good influences of great men even after their positive teaching is antiquated. Let no man be so foolish as to think that he has exhausted any subject for his generation. Virchow was not happy when he saw the young men pour into the old bottle of cellular pathology the new wine of bacteriology. Lister could never understand how aseptic surgery arose out of his work. Ehrlich would not recognize his epoch-making views on immunity when this generation has finished with them. I believe it was Hegel who said that progress is a series of negations--the denial today of what was accepted yesterday, the contradiction by each generation of some part at least of the philosophy of the last; but all is not lost, the germ plasm remains, a nucleus of truth to be fertilized by men often ignorant even of the body from which it has come. Knowledge evolves, but in such a way that its possessors are never in sure possession. "It is because science is sure of nothing that it is always advancing" (Duclaux). History is the biography of the mind of man, and its educational value is in direct proportion to the completeness of our study of the individuals through whom this mind has been manifested. I have tried to take you back to the beginnings of science, and to trace its gradual development, which is conditioned by three laws. In the first place, like a living organism, truth grows, and its gradual evolution may be traced from the tiny germ to the mature product. Never springing, Minerva-like, to full stature at once, truth may suffer all the hazards incident to generation and gestation. Much of history is a record of the mishaps of truths which have struggled to the birth, only to die or else to wither in premature decay. Or the germ may be dormant for centuries, awaiting the
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