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ons to medical science. Professor Allbutt says:-- "The little book _De abditis causis morborum_ (brief title), was not published in any form by Antony Benivieni himself, but posthumously by his brother Jerome, who found these precious notes in Antony's desk after his death, and with the hearty cooperation of a friend competent in the subject, published them in 1506 in a form which no doubt justly merits our admiration. Benivieni's chief fame for us is far more than all this; it is that he was the founder of pathological anatomy. So far as I know, he was the first to make the custom and to declare the need of necropsy to reveal what he called not exactly "the secret causes," but the hidden causes of diseases. Before Vesalius, before Eustachius, he opened the bodies of the dead as {85} deliberately and clear-sightedly as any pathologist in the spacious time of Baillie, Bright and Addison. Virchow, in his address at Rome, said Morgagni was the first pathological anatomist who, instead of asking What is disease? asked Where is it?" But Benivieni asked this question plainly before Morgagni: "Not only," says he, "must we observe the disease, but also with more diligence search out the seat of it." The precept is so important, I will quote the original words: "Oportet igitur medicum non solum morbum cognoscere, sed et locum in quo fit, diligentius perscrutari." Among the pathological reports are morbus coxae (two cases); biliary calculus (two cases); abscess of the mesentery, thrombosis of the mesenteric vessels; stenosis of the intestine; some remarkable cardiac cases, several of "polypus" (clot, which was a will-of-the-wisp to the elder pathologists); scirrhus of the pylorus, and probably another case in the colon; ruptured bowel (two cases); caries of ribs with exposure of the heart. He gives a good description of senile gangrene which even Pare did not discriminate. He seems to have had remarkable success in obtaining necropsies; concerning one fatal case he says plaintively, "Sed nescio qua superstitione versi negantibus cognatis," etc. Of another he says, "cadavere publicae utilitatis gratia inciso" (the case of cancer of the stomach). With this admirable and original leader, Italian medicine of the fifteenth century closes gloriously, to slumber for some fifty years, till the dayspring of the new learning. Of his work Malpighi says, and apparently with truth, "up to now it
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