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possible to determine exactly what constitutes the active principle in use in the milk consumed in these countries, and, as we shall see, this principle has been applied so that, at the present day, a pure fermented milk may be obtained in any country, and there is every reason to believe that should such be adopted as a general article of food, it would contribute to the prolongation of human existence. It is due to Metchnikoff, of the Pasteur Institute, that so much prominence has been given to the use of fermented milks. He gave it as his opinion[40] that senility was caused partly by auto-intoxication or by the poison derived from putrefactive micro-organisms which inhabit the digestive track. These organisms increase with age, and under certain unhealthy conditions multiply enormously, particularly in the large intestine. Having arrived at this knowledge, Metchnikoff set to work to devise some means of combating the influence of these harmful microbes, and set up the hypothesis that the tendency to longevity which is exhibited in Eastern countries is due to the consumption of lactic acid organisms in the shape of soured milk. These organisms are more powerful than those of a putrefactive character and inhibit their growth. "In the presence of such facts," says Metchnikoff, "it becomes exceedingly important to find some means of combating the intestinal putrefaction which constitutes so incontestable a source of danger. Such putrefaction is not only capable of producing diseases of the digestive tube--_enteritis_ and _colitis_--but even of becoming a source of intoxication of the organism in its most varied manifestations. "It is some years since I proposed to combat intestinal putrefaction and its injurious consequences by means of lactic ferments. I thought the acidity produced by such microbes would be much more effective in preventing the germination of putrefying microbes than the small quantity of acids produced by _Bacillus coli_. On the other hand, I had no illusion as to the difficulty sure to be encountered in any effort to introduce lactic microbes into the intestinal flora which has been preoccupied by a multitude of other microbes. To make surer of the result, I chose the lactic microbe, which is the strongest as an acid producer. It is found in the _yahourt_ (yoghourt), which originates in Bulgaria. The same bacillus has also been isolated from the _leben_ of Egypt; and it is now proved that it i
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