%.
Japanese Encephalitis - mosquito-borne (Culex tritaeniorhynchus) viral
disease associated with rural areas in Asia; acute encephalitis can
progress to paralysis, coma, and death; fatality rates 30%.
African Trypanosomiasis - caused by the parasitic protozoa Trypanosoma;
transmitted to humans via the bite of bloodsucking Tsetse flies;
infection leads to malaise and irregular fevers and, in advanced cases
when the parasites invade the central nervous system, coma and death;
endemic in 36 countries of sub-Saharan Africa; cattle and wild animals
act as reservoir hosts for the parasites.
Cutaneous Leishmaniasis - caused by the parasitic protozoa leishmania;
transmitted to humans via the bite of sandflies; results in skin
lesions that may become chronic; endemic in 88 countries; 90% of cases
occur in Iran, Afghanistan, Syria, Saudi Arabia, Brazil, and Peru; wild
and domesticated animals as well as humans can act as reservoirs of
infection.
Plague - bacterial disease transmitted by fleas normally associated
with rats; person-to-person airborne transmission also possible; recent
plague epidemics occurred in areas of Asia, Africa, and South America
associated with rural areas or small towns and villages; manifests as
fever, headache, and painfully swollen lymph nodes; disease progresses
rapidly and without antibiotic treatment leads to pneumonic form with a
death rate in excess of 50%.
Crimean-Congo hemorrhagic fever - tick-borne viral disease; infection
may also result from exposure to infected animal blood or tissue;
geographic distribution includes Africa, Asia, the Middle East, and
Eastern Europe; sudden onset of fever, headache, and muscle aches
followed by hemorrhaging in the bowels, urine, nose, and gums;
mortality rate is approximately 30%.
Rift Valley fever - viral disease affecting domesticated animals and
humans; transmission is by mosquito and other biting insects; infection
may also occur through handling of infected meat or contact with blood;
geographic distribution includes eastern and southern Africa where
cattle and sheep are raised; symptoms are generally mild with fever and
some liver abnormalities, but the disease may progress to hemorrhagic
fever, encephalitis, or ocular disease; fatality rates are low at about
1% of cases.
Chikungunya - mosquito-borne (Aedes aegypti) viral disease associated
with urban environments, similar to Dengue Fever; characterized by
sudden onset of fever, rash, and severe join