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Constant_, carrying the first permanent settlers to Jamestown, sighted the two capes at the mouth of Chesapeake Bay in April, 1607. Although these small ships carrying the first permanent settlers had a stopover in the West Indies for rest and replenishment, there had been debilitating months at sea and more than 100 emigrants to provide for in addition to the crews. With limited cargo and passenger space, water and food supplies could hardly satisfy the demand created by a hundred persons at sea for hundreds of days. Several of the emigrants died on the first voyage and the remainder disembarked poorly prepared for the new tests their constitutions would soon endure. The sea voyage of these first settlers probably exacted no heavier a death toll and caused no more suffering because the ships went by way of the Canaries and the West Indies instead of by the more northerly route by-passing the islands. A contemporary described the advantages thought to be had from the stopover in the West Indies (at the island of Nevis): We came to a bath standing in a valley betwixt two hills, where wee bathed ourselves.... Finding this place to be so convenient for our men to avoid diseases which will breed in so long a voyage, wee incamped our selves on this ile sixe dayes, and spent none of our ships victuall. Anchoring off other West Indian islands the ships were able to replenish their stores with fresh meat and fish and to replace the evil-smelling and foul water in their casks with fresh. By these measures the colonists demonstrated a concern not only for comfort but also for hygienic precautions. Later voyages during the century took anywhere from two to three months. Despite the precautions taken by some, of a rest, in the West Indies to bring about "restitution of our sick people into health by the helpes of fresh ayre, diet and the baths," the trip aboard the pestered ships continued to exact a heavy death toll and to discharge disease and diseased persons. Benefits resulting from the stopover in the Indies were countered by the considerable exposure to tropical infections. One convoy carrying colonists to Virginia in 1609 and running a southerly course through "fervent heat and loomes breezes" had many of the crew and passengers fall ill from calenture (tropical or yellow fever). Out of two ships so afflicted, thirty-two persons died and were thrown overboard. Another of these ships reported t
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