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joints may be affected, and in these cases it is often best to destroy the horse at once. The reappearance of the fistula after it has apparently healed is not uncommon. The secondary attack in these cases is seldom serious. The lesion should be carefully cleaned and afterwards injected with a solution of zinc sulphate, 20 grains to the ounce of water, every second or third day until a cure is effected. In fistula of the foot we see the same tendency toward the burrowing of pus downward to lower structures, or in some cases upward toward the coronet. Prior to the development of a quittor there is always swelling at the coronet, accompanied with heat and pain. Every effort should now be made to prevent the formation of an abscess at the point of injury. Wounds caused by nails, gravel, or any other foreign body which may have lodged in the sole of the foot should be opened at once from below, so as to allow free exit to all purulent discharges. Should the injury have occurred directly to the coronet the application of cold fomentations may prove efficient in preventing the formation of an abscess. When a quittor becomes fully established it should be treated precisely as a fistula situated in any other part of the body; that is, the sinuses should all be opened from their lowest extremities, so as to afford constant drainage. All fragments of diseased tissue should be trimmed away, antiseptic solutions injected, and, after covering the wound with a pad of oakum saturated with some good antiseptic wash, the whole foot may be carefully covered with clean bandages, which will afford valuable assistance to the healing process by excluding all dirt from the affected part. Another form of treatment for this class of infections consists in the use of bacterial vaccines. Such treatment appears to be well adapted for the purpose, and according to current veterinary literature has met with success. These vaccines are composed of several strains of the organisms usually found in these pustular infections of the horse. Two kinds of vaccines are used: First, autogenic vaccines, which consist of heated (killed) cultures of the organism or organisms which are causing the trouble and which have been isolated from the lesions; second, stock vaccines, consisting of dead organisms of certain species generally found in these lesions and which are used in diseased conditions caused by one or the other of these germs. The vaccine is ad
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