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ebrate relationships already appear. Figure 7 ii. is a cross-section, its position, being shown by cross-lines in 7 i. and 6. Note first that the epiblast along the mid-dorsal line is sinking in to form what is called the neural plate (n.p.), and simultaneously on either side of it rise the neural folds (n.f.). Now, at Figure 8, a slightly later stage is represented, and at 9 i. the inturned part is separated from the general external epiblast as the spinal cord. The remainder of the epiblast constitutes the epidermis. Section 19. Reverting to Figure 7 ii., along the dorsal side of the archenteron a thickening of its wall appears, and is gradually pinched off from it to form a cellular rod, lying along under the nervous axis and above the intestine. This is the notochord (compare Figures 8 and 9). Section 20. Finally, we note two series of buds of cells, one on either side of the archenteron in Figure 7 ii. In 8 these buds have become hollow vesicles, growing out from it, the coelomic pouches. They are further developed in 9; and in 9 ii., which is a diagrammatic figure, they are indicated by dotted lines. They finally appear to (? entirely) obliterate the segmentation cavity-- they certainly do so throughout the body; and their cavities are in time cut off from the mesenteron, by the gradual constriction of their openings. In this way the coelom (body cavity) arises as a series of hollow "archenteric" outgrowths, and ms. becomes the alimentary canal. mt.c., the metapleural canals, probably arise subsequently to, and independently of, the general coelomic space, by a splitting in the body-wall substance. Section 21. Hence, in considering the structure of amphioxus, we have three series of cells from which its tissues are developed:-- 1. The epiblast. 2. Walls of the coelomic pouches, which form (a) an inner lining to the epiblast, (b) an outer coating to the hypoblast, and (c) the mesentery (m.), by which the intestine is supported. This is the mesoblast. 3. The lining of the mesenteron, or hypoblast. From the epiblast the epidermis (not the dermis), the nervous system (including the nerves), and the sensory part of all sense organs are derived. From the mesoblast the muscles, the dermis genital and excretory organs, circulatory fluid and apparatus, any skeletal structures; and all connective tissue are derived. The mass of the body is thus evidently made of mesoblast. The hypoblas
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