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blem. (After all that is what both of us are interested in.) By the way, please send me a reprint of the paper when it comes out. I guess I am really hepped up on this, because I've just got to point out for emphasis other incidences usually of a type that involved missing a whole organ in dissections or a tissue structure in histology only on the _first_ study, and then re-reading the assignment--after knowing what to look for--and _subsequently finding it exactly where it is said to be_. (Ever hunt for an unknown quality--or quantity?) _So it was there all the time_, sloppy technique? Or is this branching at a control point? _cf._ LC: C. vs. B. p. 251. To get back to my thesis research, the pieces of equipment that I have been using in the research are fairly standard in physiological research: a Beckman spectrophotometer, a Coleman photometer, a van Slyke amino nitrogen apparatus, a Warburg respirometer, pH meters, Kjeldahls, Thunbergs, et cetera. Mostly, I'm in the process of getting used to them. Also there is a high voltage X-ray generator, U. V. source and other equipment for irradiation purposes. We also have an A. E. C. license so that we can get at least microcurie amounts of the usual isotopes for radioautographic work. Now the literature in my area is pretty controversial. (You can appreciate _that_, especially since Bergbottom at the Kaiser Wilhelm Institute bombarded you with criticisms of your theories.) Different and actually contradictory results have been obtained for the same substance in the same organism, _e. g._ alkaline phosphatase in the frog liver cell (Monnenblick, '55, Tripp, '56, and Stone, '57). To give an example, when I start a run for respiration effects using a Warburg I don't know what results to expect. Whenever this has been the case, my results have been confusing ... to say the least. On nitrogen-mustard treated cells, in some instances the controls respired significantly _more_--even with a statistical analysis of variance--in some instances the _experimentals_ respired significantly more; and in other cases the respiration for both was _exactly_ the same--even _closer_ than the expected deviations that should be found in any random population. One run, the blank run, _containing no cells_ ... and grease-free ... consumed the greatest amount of oxygen. To cut this letter short, the same inconstancies apply to other trials that I have made. Whenever I didn't know what to expe
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