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e blood. Any excessive increase from this source I have designated _leucocytosis_. In the first months of the embryo the red cell multiplies by division. In adult life the mode of its multiplication is unknown. They, also, are probably formed in the lymphatic glands and spleen. In a disease I have named _leukaemia_, the colourless blood cells increase in number enormously. In such cases there is always disease of the spleen, and very often of the lymphatic glands. These facts can hardly, I think, be interpreted in any other manner than by supposing that the spleen and lymphatic glands are intimately concerned in the production of the formed elements of the blood. By _pyaemia_ is meant pus corpuscles in the blood. But most cases of so-called pyaemia are really cases in which there is an increase of white blood corpuscles, and it is doubtful whether such a condition as pus in the blood does ever occur. In the extremely rare cases, in which pus breaks through into the veins, purulent ingredients may, without doubt, be conveyed into the blood, but in such cases the introduction of pus occurs for the most part but once, and there is no persistent pyaemia. Even when clots in veins break down and form matter like pus, it will be found that the matter is not really pus, and contains no pus cells. _Chlorosis_ is a condition in which there is a diminution of the cellular elements of the blood, due probably to their deficient formation in the spleen and lymphatic glands. _The Vital Processes and Their Relation to Disease. Inflammation_ The study of the histology of the nervous system shows that in all parts of the body a splitting up into a number of small centres takes place, and that nowhere does a single central point susceptible of anatomical demonstration exist from which the operations of the body are directed. We find in the nervous systems definite little cells which serve as centres of motion, but we do not find any single ganglion cell in which alone all movement in the end originates. The most various individual motor apparatuses are connected with the most various individual motor ganglion cells. Sensations are certainly collected in definite ganglion cells. Still, among them, too, we do not find any single ganglion cell which can be in any way designated the centre of all sensation, but we again meet with a great number of very minute centres. All the operations which have their source in the nervous sy
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