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renders the body more subject to the action of heat afterwards applied, by allowing the excitability to be accumulated. No person, I believe, ever brought on an inflammation, or inflammatory complaint, by exposure to cold, however long might have been that exposure, or however great the cold; but if a person have been out in the cold air, and afterwards come into a warm room, an inflammatory complaint will most probably be the consequence. Indeed coming out of the cold air into a moderately warm room generally produces a lively and continued warmth in the parts that have been exposed. The second general law is, that when the exciting powers have acted with violence for a considerable time, the excitability becomes exhausted, or less fit to be acted on; and this we shall be able to prove by a similar induction. Let us first examine the effects of light upon the eye: when it has acted violently for some time on the optic nerve, it diminishes the excitability of that nerve, and renders it incapable of being affected by a quantity of light, that would at other times affect it. When we have been walking out in the snow, if we come into a room, we shall scarcely be able to see any thing for some minutes. If you look stedfastly at a candle for a minute or two, you will with difficulty discern the letters of a book which you were before reading distinctly. When our eyes have been exposed to the dazzling blaze of phosphorus in oxygen gas, we can scarcely see any thing for some time afterwards, and if we look at the sun, the excitability of the optic nerve is so overpowered by the strong stimulus of his light, that nothing can be seen distinctly for a considerable time. If we look at the setting sun, or any other luminous object of a small size, so as not greatly to fatigue the eye, this part of the retina becomes less sensible to smaller quantities of light; hence when the eyes are turned on other less luminous parts of the sky, a dark spot is seen resembling the shape of the sun, or other luminous object on which our eyes have been fixed. On this account it is that we are some time before we can distinguish objects in an obscure room, after coming from broad daylight, as I observed before. We shall next consider the action of heat. Suppose water to be heated to 90 degrees, if one hand be put into it, it will appear warm; but if the other hand be immersed in water heated to 120 degrees, and then put into the water
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