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id about the beginning of the 17th century. He entered the household of the duke de Albuquerque, and after some years of service in the army received the order of Santiago in 1648. He was a favourite of Philip IV., who is reported to have collaborated with him; this rumour is not confirmed, but there is ample proof of Coello's collaboration with Calderon, Rojas Zorrilla, Solis and Velez de Guevara, the most distinguished dramatists of the age. The best of his original plays, _Los Empenos de seis horas_, has been wrongly ascribed to Calderon; it was adapted by Samuel Tuke, under the title of _The Adventures of five Hours_, and was described by Pepys as superior to _Othello_. It is an excellent example of stagecraft and animated dialogue. Coello died on the 20th of October 1652, shortly after his nomination to a post in the household of Philip IV. COELOM AND SEROUS MEMBRANES. In human anatomy the body-cavity or coelom (Gr. [Greek: koilos], hollow) is divided into the _pericardium_, the two _pleurae_, the _peritoneum_ and the two _tunicae vaginales_. The _pericardium_ is a closed sac which occupies the central part of the thorax and contains the heart. Like all the serous membranes it has a visceral and a parietal layer, the former of which is closely applied to the heart and consists of endothelial cells with a slight fibrous backing: to it is due the glossy appearance of a freshly removed heart. The parietal layer is double; externally there is a strong fibrous protective coat which is continuous with the other fibrous structures in the neighbourhood, especially with the sheaths of the great vessels at the root of the heart, with prolongations of the fascia of the neck, and with the central tendon of the diaphragm, while internally is the serous layer which is reflected from the surface of the heart, where the great vessels enter, so that everywhere the two layers of the serous membrane are in contact, and the only thing within the cavity is a drop or two of the fluid secreted by the serous walls. When the parietal layer is laid open and the heart removed by cutting through the great vessels, it will be seen that there are two lines of reflection of the serous layer, one common to the aorta and pulmonary artery, the other to all the pulmonary veins and the two venae cavae. The _pleurae_ very closely resemble the pericardium except that the fibrous outer coat of the parietal layer is not nearly as strong; it is
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