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on of what are known as antitoxins, and no more wonderful discovery has ever been made. To understand as best we may the principle involved, it is necessary to explain the process of bacterial attack. When bacteria capable of producing disease are introduced into the system, either through the mouth or into the lungs or into the blood through some skin abrasion, the bacteria, finding there a congenial habitat, thrive, grow, and multiply. In some cases, this bacterial growth results only in breaking down the cell tissues at the point or in the vicinity of the place where growth occurs; for instance, if a cut is made with a dirty knife, that is, one carrying bacteria on the blade, and is not immediately washed out with an antiseptic solution, bacteria will grow and pus will form in the cut. Similarly, a splinter, if not removed and cleansed, will produce a pus-forming wound. But unless a very extensive suppuration starts, the difficulty is all local. So it is with consumption, when the bacteria are localized in the lungs and by their growth destroy the lung tissue without, at least for many weeks, affecting the general health. There are germs, however, like typhoid fever and diphtheria, which do not produce any particular local disturbance with the growth of bacteria, but the whole body becomes sick, the circulation of the blood is affected, and a general disturbance ensues. This is due to the action of a poison, called a toxin, which is set free as a result of the growth of the bacteria in some one part of the body, which poison is then carried by the blood throughout the entire system, inducing fever and a general debility. Just how these toxins are formed is not certain. They are not the bacteria themselves. This we know because the disease-producing bacteria can be grown in broth and the mixture can be strained through fine porcelain, fine enough to strain out the bacteria. Yet it has been found that the clear liquid passing the porcelain filter is capable of producing disease and is a deadly poison without the presence of any bacteria at all. During the incubation period of a disease, as, for example, in the three-week period when typhoid fever is developing, these poisons are being formed and are being scattered through the body, and it is during this time that the fight takes place between these poisonous forces and the defending forces always present in the human system. As already pointed out, these defensive
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