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inated in Europe itself. The corruption of the atmosphere came from the East; but the disease itself came not upon the wings of the wind, but was only excited and increased by the atmosphere where it had previously existed. This source of the black plague was not, however, the only one; for, far more powerful than the excitement of the latent elements of the plague by atmospheric influences was the effect of the contagion communicated from one people to another, on the great roads, and in the harbors of the Mediterranean. From China, the route of the caravans lay to the north of the Caspian Sea, through Central Asia to Tauris. Here ships were ready to take the produce of the East to Constantinople, the capital of commerce and the medium of connection between Asia, Europe, and Africa. Other caravans went from India to Asia Minor, and touched at the cities south of the Caspian Sea, and lastly from Bagdad, through Arabia to Egypt; also the maritime communication on the Red Sea, from India to Arabia and Egypt, was not inconsiderable. In all these directions contagion made its way; and doubtless Constantinople and the harbors of Asia Minor are to be regarded as the _foci_ of infection; whence it radiated to the most distant seaports and islands. To Constantinople the plague had been brought from the northern coast of the Black Sea, after it had depopulated the countries between those routes of commerce and appeared as early as 1347, in Cyprus, Sicily, Marseilles, and some of the seaports of Italy. The remaining islands of the Mediterranean, particularly Sardinia, Corsica, and Majorca, were visited in succession. _Foci_ of contagion existed also in full activity along the whole southern coast of Europe, when, in January, 1348, the plague appeared in Avignon, and in other cities in the South of France and North of Italy, as well as in Spain. The precise days of its eruption in the individual towns are no longer to be ascertained; but it was not simultaneous; for in Florence the disease appeared in the beginning of April; in Cesena, the 1st of June; and place after place was attacked throughout the whole year; so that the plague, after it had passed through the whole of France and Germany, where, however, it did not make its ravages until the following year, did not break out till August in England; where it advanced so gradually that a period of three months elapsed before it reached London. The northern kingdoms were att
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