dard, the
inherited injuries in Brown-Sequard's guinea-pigs are only exceptional
cases of quasi-inheritance, and are not necessarily indicative of any
general rule affecting true inheritance.

FOOTNOTES:

[54] A very able anatomist of my acquaintance denies the inheritance of
mutilations and injuries, although he strongly believes in the
inheritance of the effects of use and disuse.

[55] _Variation of Animals and Plants under Domestication_, i. 467-469.
Lost toes were only seen by Dr. Dupuy in three young out of two hundred.
Obersteiner found that most of the offspring of his epileptic
guinea-pigs were injuriously affected, being weakly, small, paralysed in
one or more limbs, and so forth. Only two were epileptic, and both were
weakly and died early (Weismann's _Essays_, p. 311). A morbid condition
of the spinal cord might affect the hind limbs especially (as in
paraplegia) and might occasionally cause loss of toes in the embryo by
preventing development or by ulceration. Brown-Sequard does not say that
the defective feet were on the same side as in the parents (_Lancet_,
Jan., 1875, pp. 7, 8).

[56] _Variation of Animals and Plants under Domestication_, ii. 57.

[57] _Ibid._, ii. 392. Perhaps it might be better to suppose that the
_best_ gemmules were sacrificed in repairing the injured _nerve_, and
hence only inferior substitutes were left to take their place, and could
only imperfectly reproduce the injured part of the nervous system in
offspring.

[58] Hence perhaps Mr. Spencer's error in representing the epileptic
liability as permanent and as coming on _after_ healing (_Factors of
Organic Evolution_, p. 27).

[59] It is not claimed that the imperfect foot was on the same side of
the body as in the parent, and where parents had lost _all_ the toes of
a foot, or the whole foot, the few offspring affected usually had lost
only two toes out of the three, or only a part of one or two or three
toes. Sometimes the offspring had toes missing on _both_ hind feet,
although the parent was only affected in _one_. _One_ diseased ear and
eye in the parent was "generally" or "always" succeeded by _two_ equally
affected ears and eyes in the offspring (cf. _Pop. Science Monthly_, New
York, xi. 334). The important law of inheritance at corresponding
periods was also set aside. Gangrene or inflammation commenced in both
ears and both eyes soon after birth (pointing possibly to infection of
some kind); the epileptic perio