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into the same inorganic substances from whence all but an inappreciable fraction of its substance demonstrably originated, so that the actual wanderings of matter are as remarkable as the transmigrations of the soul fabled by Indian tradition. But before death has occurred, in the one sex or the other, and in fact in both, certain products or parts of the organism have been set free, certain parts of the organisms of the two sexes have come into contact with one another, and from that conjunction, from that union which then takes place, there results the formation of a new being. At stated times the mare, from a particular part of the interior of her body, called the ovary, gets rid of a minute particle of matter comparable in all essential respects with that which we called a cell a little while since, which cell contains a kind of nucleus in its centre, surrounded by a clear space and by a viscid mass of protein substance (Figure 2); and though it is different in appearance from the eggs which we are mostly acquainted with, it is really an egg. After a time this minute particle of matter, which may only be a small fraction of a grain in weight, undergoes a series of changes,--wonderful, complex changes. Finally, upon its surface there is fashioned a little elevation, which afterwards becomes divided and marked by a groove. The lateral boundaries of the groove extend upwards and downwards, and at length give rise to a double tube. In the upper smaller tube the spinal marrow and brain are fashioned; in the lower, the alimentary canal and heart; and at length two pairs of buds shoot out at the sides of the body, which are the rudiments of the limbs. In fact a true drawing of a section of the embryo in this state would in all essential respects resemble that diagram of a horse reduced to its simplest expression, which I first placed before you (Figure 1). Slowly and gradually these changes take place. The whole of the body, at first, can be broken up into "cells," which become in one place metamorphosed into muscle,--in another place into gristle and bone,--in another place into fibrous tissue,--and in another into hair; every part becoming gradually and slowly fashioned, as if there were an artificer at work in each of these complex structures that we have mentioned. This embryo, as it is called, then passes into other conditions. I should tell you that there is a time when the embryos of neither dog, nor horse, nor po
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