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xtending up to the knee. The whole limb was bronzed in appearance. There was no special discoloration about the wound; in fact, the swelling disguised this to such an extent that it was impossible to determine exactly where the fangs had entered. The pulse was scarcely perceptible at the wrist; the heart was beating with excessive rapidity. The patient was suffering great pain. His mind was clear, but he was oppressed with a dreadful anxiety. Up to the time I saw him he had received absolutely no treatment, excepting the application of a cactus poultice to the leg, since there was no whisky at the ranch where he was wounded. I at once made free incisions, five or six in number, from one to two inches in depth, and about three inches in length. These cuts gave him very little pain, nor was there much bleeding, though there was an enormous amount of serous oozing. Into these wounds was poured a fifteen per cent. solution of permanganate of potassium, and fully half an hour was devoted to kneading this drug into the tissues. In addition I made many hypodermic injections into all portions of the swollen tissue, but particularly about the wound. Since there was no very distinct line of demarkation between the swollen and healthy tissue, I did not, as in other cases, endeavor to prevent the extension of the cellular involvement by a complete circle of hypodermic injections. I employed, in all, about forty grains of the permanganate. In addition to the local treatment I pushed stimulation, employing carbonate of ammonium and whisky. By means of diuretics and laxatives the kidneys and bowels were encouraged to eliminate as much of the poison as possible. The patient went on to uninterrupted recovery. The wound healed with very little sloughing. The patient returned to his work in about a month. The cure of this case was regarded by the cow boys as most exceptional, since, in their experience, similar cases, even though very freely stimulated, had not recovered. Some time later I was called to see a girl, aged 14, who was struck by a rattlesnake, fifty-six miles from Fort Fetterman. There was some trouble about procuring relays, and I was compelled to ride the same horse all the way out. This took a little short of five hours. This, together with the time consumed in sending me word, caused an interval of about twenty hours between the infliction of the injury and the time I saw the patient. I found the fangs had entered on e
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