ely covers the body; not
being confined exclusively to the skin, but frequently extending to the
mouth and throat, and even to the external membrane of the eye.

In the course of two or three days from their first appearance the
little pimples, increasing in size, will be found to contain a thin
transparent fluid, to pit or become depressed in their centre, and the
skin in the spaces between them will be found red. On the seventh or
eighth day from the commencement of the fever, the fluid contained in
the pimples will be no longer transparent, but opaque; and they will
consequently appear white, or of a light straw colour. Each pimple or
pock will be no longer depressed in its centre, but will become raised
and pointed, being more fully distended by the increased quantity of
fluid within; and the skin around each pock will now be of a bright
crimson. The head, face, hands, and wherever else the eruption shows
itself, gradually swell; and the eyelids are often so much distended as
to close the eyes and produce temporary blindness. There will always at
this time be some degree of fever present, and its amount will vary
with the circumstances of each individual ease. The skin too will be
very tender, so much so sometimes as greatly to harass and distress the
child.

On the eleventh day the swelling and inflam of the skin of the body
and face subside; the pimples upon these parts dry up and form scabs,
which fall off about the fourteenth or fifteenth day. Those on the
hands, as they come out later, commonly continue a short time longer.
The eruption leaves behind, in some cases, the peculiar marks of the
disease; and in others merely discoloured spots, which disappear in the
progress of a short time.

The natural small-pox is sometimes much more severe in its character
than the foregoing, and what is called confluent small-pox is said to
exist. This form will be marked by great constitutional disturbance,
and the eruption coming out earlier than in the milder form; instead of
being distinct, that is, each pimple standing distinct and separate
one from the other, they will coalesce, and appear flat and doughy, not
prominent: they will more particularly run into each other on the face,
where they will form one continuous bag, which soon becoming a sore,
will discharge copiously.

SMALL-POX IN THE VACCINATED.--When small-pox occurs to those that have
been formerly vaccinated, the disease, in almost every instance, is
mu