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an, to whose kindness I was at that time deeply indebted, informed me that such a termination of my case was not impossible, though likely to be forestalled by a different termination in the event of my continuing the use of opium. Opium therefore I resolved wholly to abjure as soon as I should find myself at liberty to bend my undivided attention and energy to this purpose. It was not, however, until the 24th of June last that any tolerable concurrence of facilities for such an attempt arrived. On that day I began my experiment, having previously settled in my own mind that I would not flinch, but would "stand up to the scratch" under any possible "punishment." I must premise that about 170 or 180 drops had been my ordinary allowance for many months; occasionally I had run up as high as 500, and once nearly to 700; in repeated preludes to my final experiment I had also gone as low as 100 drops; but had found it impossible to stand it beyond the fourth day--which, by the way, I have always found more difficult to get over than any of the preceding three. I went off under easy sail--130 drops a day for three days; on the fourth I plunged at once to 80. The misery which I now suffered "took the conceit" out of me at once, and for about a month I continued off and on about this mark; then I sunk to 60, and the next day to--none at all. This was the first day for nearly ten years that I had existed without opium. I persevered in my abstinence for ninety hours; i.e., upwards of half a week. Then I took--ask me not how much; say, ye severest, what would ye have done? Then I abstained again--then took about 25 drops then abstained; and so on. Meantime the symptoms which attended my case for the first six weeks of my experiment were these: enormous irritability and excitement of the whole system; the stomach in particular restored to a full feeling of vitality and sensibility, but often in great pain; unceasing restlessness night and day; sleep--I scarcely knew what it was; three hours out of the twenty-four was the utmost I had, and that so agitated and shallow that I heard every sound that was near me. Lower jaw constantly swelling, mouth ulcerated, and many other distressing symptoms that would be tedious to repeat; amongst which, however, I must mention one, because it had never failed to accompany any attempt to renounce opium--viz., violent sternutation. This now became exceedingly troublesome, sometimes lasting
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