accompanied by vomiting. It dies
of respiratory paralysis, death many times being hastened by the asphyxia
following the vomiting.

_Treatment._--The animal, if found down, should be turned so that its head
is uphill in order to relieve the lungs. Many cases will recover with no
further treatment. Nearly all cases will recover if a hypodermic injection
is given immediately of physostigmin salicylate 1 grain, pilocarpin
hydrochlorid 2 grains, strychnin sulphate 1/2 grain.

LOCO.

The loco plants have caused especially heavy losses of cattle, horses, and
sheep. They grow in the semiarid regions of the West and sometimes in great
luxuriance. The best known are the "blue loco," the "woolly loco" or
"purple loco," and the "white loco" or "rattle-weed." The blue loco is
common in parts of New Mexico, Arizona, and Utah. It affects both horses
and cattle. The purple loco, _Astragalus mollissimus_, is common in Texas
and the adjoining States and extends north as far as Nebraska and Colorado.
It is especially destructive to horses. The white loco, _Oxytropis
lamberti_, is still more widely distributed, being found in the plains
region from Alaska to Mexico and west of the Rocky Mountains to central
Utah. The white loco is much more important than the purple loco, for it
affects not only horses but cattle and sheep. These plants belong to the
pea family, and there are a number of other species of this family that are
loco plants and produce the same symptoms.

_Symptoms._--Loco poisoning is a chronic condition and symptoms are shown
only after somewhat prolonged feeding. The condition is one of cumulative
poisoning, and animals sometimes decline very rapidly after the first
symptoms appear. In many cases animals acquire a habit of eating loco and
prefer it to any other feed. The poison affects the central nervous system.
There is a lack of muscular coordination and the animal performs very
erratic movements. In the later stages the animal becomes emaciated and
eventually dies of starvation.

_Treatment._--Locoed animals are badly constipated, and it is important
that this condition should be remedied at the start. Any purgative can be
used, but Epsom salt has been found especially effective. If locoed animals
can be turned into a field of alfalfa, a large proportion of them will
recover with no further treatment. Recovery may be aided by giving cattle,
hypodermically, daily doses of three-twentieths to four-twentieths of a