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ter on what soil the plants are grown. Having treated at some length of the various parts of the tobacco plant--stalk, leaves, flowers, capsules and suckers we come now to its nicotine properties. The tobacco plant, as is well known, produces a virulent poison known as Nicotine. This property, however, as well as others as violent is found in many articles of food, including the potato together with its stalk and leaves; the effects of which may be experienced by chewing a small quantity of the latter. The New Edinburgh Encyclopedia says: "The peculiar effect produced by using tobacco bears some resemblance to intoxication and is excited by an essential oil which in its pure state is so powerful as to destroy life even in very minute quantity." Chemistry has taught us that nicotine is only one among many principles which are contained in the plant. It is supposed by many but not substantiated by chemical research that nicotine is not the flavoring agent which gives tobacco its essential and peculiar varieties of odor. Such are most probably given by the essential oils, which vary in amount in different species of the plant. An English writer says: "Nicotine is disagreeable to the habitual smoker, as is proved by the increased demand for clean pipes or which by some mechanical contrivance get rid of the nicotine." The late Dr. Blotin tested by numerous experiments the effects of nicotine on the various parts of the organization of man. While the physiological effects of nicotine may be interesting to the medical practitioner, they will hardly interest the general reader unless it can be shown that the effects of nicotine and tobacco should be proved to be identical. We are loth to leave this subject, however, as it is so intimately connected with the history of the plant, without treating somewhat of its medicinal properties which to many are of more interest than its social qualities. The Indians not only used the plant socially, religiously, but medicinally. Their Medicine men prescribed its use in various ways for most diseases common among them. The use thus made of the plant attracted the attention of the Spanish and English, far more than its use either as a means of enjoyment or as a religious act. When introduced to the Old World, its claims as a remedy for most diseases gave it its popularity and served to increase its use. It was styled "_Sana sancta Indorum_--"
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