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diseases literally plant their seeds, grow, and shake abroad new germs, which, meeting in the human body their proper food and temperature, finally take possession of whole populations. There is nothing to my knowledge in pure chemistry which resembles the power of propagation and self-multiplication possessed by the matter which produces epidemic disease. If you sow wheat you do not get barley; if you sow small-pox you do not get scarlet-fever, but small-pox indefinitely multiplied, and nothing else. The matter of each contagious disease reproduces itself as rigidly as if it were (as Miss Nightingale puts it) dog or cat. Parasitic Diseases of Silkworms. Pasteur's Researches. It is admitted on all hands that some diseases are the product of parasitic growth. Both in man and in lower creatures, the existence of such diseases has been demonstrated. I am enabled to lay before you an account of an epidemic of this kind, thoroughly investigated and successfully combated by M. Pasteur. For fifteen years a plague had raged among the silkworms of France. They had sickened and died in multitudes, while those that succeeded in spinning their cocoons furnished only a fraction of the normal quantity of silk. In 1853 the silk culture of France produced a revenue of one hundred and thirty millions of francs. During the twenty previous years the revenue had doubled itself, and no doubt was entertained as to its further augmentation. The weight of the cocoons produced in 1853 was 26,000,000 kilogrammes; in 1865 it had fallen to 4,000,000, the fall entailing, in a single year, a loss of 100,000,000 francs. The country chiefly smitten by this calamity happened to be that of the celebrated chemist Dumas, now perpetual secretary of the French Academy of Sciences. He turned to his friend, colleague, and pupil, Pasteur, and besought him, with an earnestness which the circumstances rendered almost personal, to undertake the investigation of the malady. Pasteur at this time had never seen a silkworm, and he urged his inexperience in reply to his friend. But Dumas knew too well the qualities needed for such an enquiry to accept Pasteur's reason for declining it. 'Je mets,' said he, 'un prix extreme a voir votre attention fixee sur la question qui interesse mon pauvre pays; la misere surpasse tout ce que vous pouvez imaginer.' Pamphlets about the plague had been showered upon the public, the monotony of waste paper being b
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