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1 II. ON CERTAIN MISTAKES OF SCIENTISTS - - 12 III. AN EIGHTEENTH-CENTURY VIVISECTOR - - - 22 IV. MAGENDIE AND HIS CONTEMPORARIES - - - 29 V. A VIVISECTOR'S REMORSE - - - - 47 VI. IS TORTURE JUSTIFIED BY UTILITY? - - 57 VII. THE COMMENCEMENT OF AGITATION - - - 66 VIII. ATTAINMENT OF REGULATION IN ENGLAND - - 88 IX. A GREAT PROTESTANT - - - - 113 X. THE VIVISECTION REPORT OF 1912 - - - 127 XI. THE ANAESTHETIC DELUSION - - - 149 XII. THE VIVISECTION OF TO-DAY - - - 162 XIII. WHAT IS VIVISECTION REFORM? - - - 196 XIV. THE WORK OF REFORM SOCIETIES - - - 216 XV. UNFAIR METHODS OF CONTROVERSY - - - 228 XVI. RESEARCH WITHOUT VIVISECTION - - - 254 XVII. THE FUTURE OF VIVISECTION - - - 276 XVIII. THE FINAL PHASE: EXPERIMENTATION ON MAN - 289 XIX. CONCLUSION - - - - - 326 APPENDIXES - - - - 333-364C INDEX - - - - 365-369 PRESS NOTICES - - - - 371-374 INTRODUCTION It is now somewhat over a third of a century since my attention was specially directed to the abuses of animal experimentation. In January, 1880, a paragraph appeared in a morning paper of New York referring to the late Henry Bergh. With his approval a Bill had come before the legislature of the State of New York providing for the abolition of all experiments upon living animals--whether in medical colleges or elsewhere--on the ground that they were without benefit to anybody, and demoralizing alike to the teacher and student. As I dropped the paper, it occurred to me that the chances of success would have been far greater if less had been asked. That certain vivisections were atrocious was undoubtedly true; but, on the other hand, there were some experiments that were absolutely painless. Would it not be wiser to make some distinctions? The attempt was made. An article on the subject was at once begun, and in July of the same year it was published in Scribner's Magazine, the predecessor of the Century. So far as known, it was the first argument that ever found ex
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