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abundant evidence of its sensibility to suffering by its struggles and cries. The experimenter might try to believe that the pain was slight, but he never disputed its existence. To-day, all this is changed. As much or as little of the anaesthetic may be given as the vivisector desires, and yet he may declare that "ANAESTHETICS WERE USED," no matter how slight the degree of sensibility thus induced. It is a known fact that a dog is very susceptible to the action of chloroform, so that during its administration death frequently occurs. Sir Thornley Stoker, the President of the Royal Academy of Medicine in Ireland, and for many years a teacher of science, testified before the Commission that a dog's heart is very weak and irregular, and susceptible to the poisonous influence of chloroform. Over and over again he expresses the doubts that arise concerning the administration of chloroform. "I fear that, particularly in the case of dogs, ANAESTHESIA IS NOT ALWAYS PUSHED TO A SUFFICIENT EXTENT, as these animals often die from the effects of the anaesthetic if given to a full extent.... I am never sure, if I give a dog chloroform, that I will not kill it.... THE ANAESTHESIA CANNOT BE COMPLETE if the dog lives as long as is necessary for some of these experiments." Even for one hour he believes it would be generally impossible to keep a dog alive under full anaesthesia. On the other hand, Dr. Starling declared that "there is no difficulty in keeping an animal alive as long as you like," and Sir Victor Horsley affirmed that one could keep a dog under chloroform "FOR A WEEK, if you only take the trouble."[1] [1] See Minutes of Evidence, November 13, 1907, Q. 15,649. The discrepancy here would seem insurmountable. May it not be more in appearance than in reality? One man tells me that arsenic is a poison, very liable to cause death. Another affirms that he has taken it for days in succession, and has experienced no unpleasant results. Both statements can be true, for they need not refer to the same amount. In the modern laboratory there is little danger that the animals will succumb to the effects of anaesthetic. Assuredly we may question the completeness of that insensibility which Sir Victor Horsley apparently declares may be maintained for a week. The use of the substance known as CURARE, either alone or in connection with anaesthetics or narcotics, was naturally a subject of passing inquiry. So slight is the
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