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a river god which used to stand in the Monti, and Pasquino, beneath whom the Roman children used to be told that the book of all wisdom was buried for ever. In the Region of Parione stands the famous Cancelleria, a masterpiece of Bramante's architecture, celebrated for many events in the later history of Rome, and successively the princely residence of several cardinals, chief of whom was that strong Pompeo Colonna, the ally of the Emperor Charles the Fifth, who was responsible for the sacking of Rome by the Constable of Bourbon, who ultimately ruined the Holy League, and imposed his terrible terms of peace upon Clement the Seventh, a prisoner in Sant' Angelo. Considering the devastation and the horrors which were the result of that contest, and its importance in Rome's history, it is worth while to tell the story again. Connected with it was the last great struggle between Orsini and Colonna, Orsini, as usual, siding for the Pope, and therefore for the Holy League, and Colonna for the Emperor. Charles the Fifth had vanquished Francis the First at Pavia, in the year 1525, and had taken the French King prisoner. A year later the Holy League was formed, between Pope Clement the Seventh, the King of France, the Republics of Venice and Florence, and Francesco Sforza, Duke of Milan. Its object was to fight the Emperor, to sustain Sforza, and to seize the Kingdom of Naples by force. Immediately upon the proclamation of the League, the Emperor's ambassadors left Rome, the Colonna retired to their strongholds, and the Emperor made preparations to send Charles, Duke of Bourbon, the disgraced relative of King Francis, to storm Rome and reduce the imprisoned Pope to submission. The latter's first and nearest source of fear lay in the Colonna, who held the fortresses and passes between Rome and the Neapolitan frontier, and his first instinct was to attack them with the help of the Orsini. But neither side was ready for the fight, and the timid Pontiff eagerly accepted the promise of peace made by the Colonna in order to gain time, and he dismissed the forces he had hastily raised against them. [Illustration: PALAZZO MASSIMO ALLE COLONNA] [Illustration: PONTE SISTO From a print of the last century] They, in the mean time, treated with Moncada, Regent of Naples for the Emperor, and at once seized Anagni, put several thousand men in the field, marched upon Rome with incredible speed, seized three gates in the night, and
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