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promising British port in the Pacific. During this same year, Dr. John Rae, by sledge journeys of more than 1,200 miles, explored the northernmost region, Boothia, wherein was determined the northern magnetic pole. [Sidenote: Ether in surgery] [Sidenote: Chloroform] On October 16, Dr. J.C. Warren of Boston, to whom Drs. Wells and Morton had communicated their discoveries with sulphuric ether, demonstrated the potency of the drug in a public test. A severe operation was performed at the Boston Hospital, in the presence of some of the foremost medical men of the city, while the patient remained unconscious. The news was heralded abroad and was received by medical men throughout the world as a new revelation. Dr. Oliver Wendell Holmes, the famous physician and author, named the new method "Anaesthesia." The credit of the new discovery was claimed forthwith by several persons--notably by Dr. Charles T. Jackson of Boston, and Dr. Crawford W. Long of Alabama. A few months after the value of ether in surgery had come to be clearly recognized, a Scotch surgeon, Sir J.V. Simpson, discovered that chloroform could be administered with analogous effect. [Sidenote: Mexican war begun] [Sidenote: Mexican success] [Sidenote: American reverse at Fort Brown] [Sidenote: Palo Alto] [Sidenote: Resaca de la Palma] [Sidenote: Invasion of Mexico] In the United States, during this period, the long-expected war with Mexico was well under way. By a joint resolution of Congress, Texas had at last been admitted into the Union. General Taylor took position in Texas, opposite Matamoras on the Rio Grande, where the Mexican troops were gathering. Taylor presently moved his troops to Point St. Isabel. There a fleet of seven ships brought supplies. Leaving a part of his force there, he marched to a point on the Rio Grande opposite Matamoras, where he built Fort Brown, named after Major Brown, whom he left in command. The ground was malarious, and many soldiers died of disease. On April 12, the Mexican general, Ampudia, moved forward with a strong force to drive Taylor beyond the Rio de la Nueces. Ampudia demanded that Taylor should withdraw within twenty-four hours, but Taylor refused to leave what he claimed to be the soil of the United States. Ampudia hesitated, and General Arista was appointed in his place. Learning that two vessels with supplies for the Mexicans were about to enter the Rio Grande, Taylor caused the river to be
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