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cially in our Public Schools. VI. It is not in accord with scientific accuracy to contend for unlimited freedom of painful experimentation, on the ground of its vast utility to humanity in the discovery of new methods for the cure of disease. On the contrary, so far as can be discovered by a careful study of English mortality statistics, physiological experiments upon living animals for fifty years back have in no single instance lessened the fatality of any disease below its average of thirty-five years ago. VII. Vivisection, involving the infliction of pain is, even in its best possible aspect, a necessary evil, and ought at once to be restricted within the narrowest limits, and placed under the supervision of the State. APPENDIX. I. For reasons sufficiently stated in the preceding pages, the writer does not advocate the total abolition of all experimentation. It is only fair to acknowledge, however, that very strong and weighty arguments in favor of legal repression have been advanced both in this country and abroad, some of which are herewith presented, as the other side of the question. The cause of abolition has no more earnest and eloquent advocate than Miss Frances Power Cobbe of England. Through innumerable controversies with scientific men in the public journals, magazines and reviews, she has presented in awful array, the abuses of unlimited and uncontrolled experimentation on the continent of Europe, and the arguments in favor of total repression. The following letters, extracts from her public correspondence, will indicate her position. TENDER VIVISECTION. (TO THE EDITOR OF THE "SCOTSMAN.") 1, Victoria Street, London, S. W., January 10, 1881. SIR.--An Italian pamphlet, _Dell'Azione del Dolore sulla Respirazione_ (The Action of Pain on Respiration), has just reached my hands, and as it is, I think, quite unknown in this country, I will beg you to grant me space for a few extracts from its pages. The pamphlet is by the eminent physiologist, Mantegazza, and was published by Chiusi, of Milan. Having explained the object of his investigations to be the effects of pain on the respiratory organs, the Professor describes (p. 20) the methods he devised for the production of such pain. He found the best to consist in "planting nails, sharp and numerous, through the feet of the animal in such a manner as to render
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