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tonio Musa Brasavola (sometimes written Brasovola), whose years run with the century. His studies were made with the famous Leonicenus at Ferrara. He became the physician in ordinary and personal friend of Hercules II, Duke of Este, and accompanied him to France when the Duke espoused the daughter of Louis XII. He was at various times the physician to four Popes and was called in consultation to Henry VIII of England and Francis I of France. He devoted himself particularly to medical botany and pharmacology and was one of the first to hold a professorship in these subjects. He was well known for his life-saving practice of tracheotomy and he restored _paracentesis thoracis_ as a standard remedy. He introduced the use of _radix chinae_, a kind of smilax related to sarsaparilla, and put _lignum guiaci_ into the pharmacology of the day. He wrote a series of monographs on botanical subjects which have given him an enduring place in the history of that time. A distinguished group of men were near the Popes in Rome at this time with whom Brasavola was in close relations. They included Eustachius the great anatomist, Columbus, discoverer of the circulation in the lungs, Caesalpinus and Fallopius, who was a professor at the University of Bologna, that city being at this time in the Papal States. One of the great Renaissance physicians and surgeons well known in our histories of medicine for an important contribution to the treatment of gunshot wounds, is Alfonso Ferri, a Neapolitan, who, after some years of professorship in surgery in Naples, became the physician of Pope Paul III. His book, which is founded on his "experience at home and at war," went through a number of editions at Rome, at Antwerp and Frankfurt and other places, and he was evidently widely read and considered an important authority. He invented some instruments for the removal of bullets and has many practical hints with regard to the treatment of gunshot wounds. He was the professor of surgery at the Sapienza, {447} Rome, and has written a volume on the carunculae, or hard multiplex tumors, which arise at the vesical neck. Silvius Zeffiri, another of the physicians of Pope Paul III, is the author of a volume on "Putrefaction or The Best Method of Protracting Life," which was published at Rome in 1536. Zeffiri seems to have anticipated the modern popular notion of the putrefactive conditions in the human system as one of the most important factors in shor
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