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orehead and eyes, in the back and thighs, and often in the calves. The face is flushed and slightly swollen--particularly the upper lip--and the eyes are bloodshot, and gradually, in the course of thirty-six hours, the whites become yellowish. This is one of the most distinguishing features of the fever, but is often absent in children. The tongue is coated, there are loss of appetite, lassitude, sore throat, and constipation. In the beginning the temperature ranges from 101 deg. to 103 deg. F., or in severe cases as high as 105 deg. or 106 deg. F., and the pulse from 110 to 120 beats a minute. The fever continues for several days--except in mild cases--but the pulse usually falls before the temperature does. For example, the temperature may rise a degree during the third day to 103 deg. F., while the pulse falls ten or more beats at the same time and may not be over 70 or 80, while the temperature is still elevated. This is another peculiar feature of the disease. Vomiting often increases on the second or third day, and the dreaded "black vomit" may then occur. This presents the appearance of coffee grounds or tarry matter and, while a dangerous symptom, does not by any means presage a fatal ending. The black color is due to altered blood from the stomach, and bleeding sometimes takes place from the nose, throat, gums, and bowels, with black discharges from the latter. The action of the kidneys is usually interfered with, causing diminution in the amount of urine. It is extremely important to pay regard to this feature, because failure of the patient to pass a proper amount of urine calls for prompt action to avert fatal poisoning from retained waste matters in the blood. The normal amount of urine passed in twenty-four hours in health is over three pints, and while not more than two-thirds of this amount could be expected to be passed by a fever patient, yet in yellow fever the passage of urine may be almost or wholly suppressed. The course of the disease varies greatly. In children--especially of the Creoles--it is frequently so mild as to pass unnoticed. In adults the fever may only last a few hours, or two or three days, with gradual recovery from the various symptoms, and yellowness of the skin lasting for some time. This is not seen readily during the stage of fever when the surface is reddened, but at that time may be detected by pressure on the skin for a minute, when the skin will present a yellow hue on removi
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