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n the experiments. But Abbe Spallanzani thought that he detected such slips in Needham's experiment. The possibility of such slips might come in several ways: the contents of the jar might not have been boiled for a sufficient length of time to kill all the germs, or the air might not have been excluded completely by the sealing process. To cover both these contingencies, Spallanzani first hermetically sealed the glass vessels and then boiled them for three-quarters of an hour. Under these circumstances no animalcules ever made their appearance--a conclusive demonstration that rendered Needham's grounds for his theory at once untenable.(2) Allied to these studies of spontaneous generation were Spallanzani's experiments and observations on the physiological processes of generation among higher animals. He experimented with frogs, tortoises, and dogs; and settled beyond question the function of the ovum and spermatozoon. Unfortunately he misinterpreted the part played by the spermatozoa in believing that their surrounding fluid was equally active in the fertilizing process, and it was not until some forty years later (1824) that Dumas corrected this error. THE CHEMICAL THEORY OF DIGESTION Among the most interesting researches of Spallanzani were his experiments to prove that digestion, as carried on in the stomach, is a chemical process. In this he demonstrated, as Rene Reaumur had attempted to demonstrate, that digestion could be carried on outside the walls of the stomach as an ordinary chemical reaction, using the gastric juice as the reagent for performing the experiment. The question as to whether the stomach acted as a grinding or triturating organ, rather than as a receptacle for chemical action, had been settled by Reaumur and was no longer a question of general dispute. Reaumur had demonstrated conclusively that digestion would take place in the stomach in the same manner and the same time if the substance to be digested was protected from the peristalic movements of the stomach and subjected to the action of the gastric juice only. He did this by introducing the substances to be digested into the stomach in tubes, and thus protected so that while the juices of the stomach could act upon them freely they would not be affected by any movements of the organ. Following up these experiments, he attempted to show that digestion could take place outside the body as well as in it, as it certainly should if
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