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entioned, upon which she observed, "I cannot take that disease, for I have had the cowpox." This was sufficient to excite the attention of Jenner, and the incident never escaped his recollection. It is easier to conceive than to express the emotions which would naturally spring from reflection on such a subject; his benevolent feelings were at once aroused to full activity; he pictured to himself all the horrors of that pestilential and most loathsome disease, disfiguring Nature's greatest work, slaying thousands upon thousands, and he was yet sufficiently young to recollect the severity of discipline to which he had himself submitted in the process preparatory to the practice of inoculation, which, to use his own words, in that day was no less than that of "bleeding till the blood was thin; purging till the body was wasted to a skeleton; and starving on vegetable diet to keep it so." The patience manifested by Jenner in the prosecution of his inquiry into the cowpox, the scrutiny to which he subjected every appearance that presented itself, and the fortitude with which he withstood every untoward circumstance entitle him to all praise and show forth his great capabilities for conducting a philosophical investigation. He divested the subject of all its difficulties and obscurities, and gave to "vague, inapplicable and useless rumor the certainty and precision of scientific knowledge." The extent of his anticipations upon this truly momentous subject do not appear to have been fully stated until 1780, ten years subsequent to his mention of it to John Hunter. He then confidentially disclosed to his intimate friend, Edward Gardner--who gave evidence upon the subject before the committee of the House of Commons--the opinions he entertained upon the natural history of the cowpox; dated its origin from the diseased heel of a horse; alluded to the different diseases with which the hands of the milkers became affected from handling the infected cows; distinguished that which was calculated to afford security against the smallpox; and divulged the hope he entertained of being able finally to eradicate that disease from the face of the globe. Doctor Baron has recorded the remarkable words with which this important communication was made: "I have intrusted a most important matter to you, which I firmly believe will prove of essential benefit to the human race. I know you, and should not wish what I have stated to be brought into
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