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ul and honorable positions in the world. Living in a rapidly-growing Western community, they had every prospect of growing up to honorable usefulness, a comfort to their parents, a blessing to the world, and capable of enjoying life in the highest degree. But suddenly certain manifestations appeared which gave rise to grave apprehensions on the part of the parents. It was observed that the elder of the little boys no longer played about with that nimbleness which he had formerly shown, but seemed slow and stiff in his movements. Sometimes, indeed, he would stagger a little when he walked. Soon, also, his speech became affected in some degree; he mumbled his words and could not speak distinctly. In spite of all that could be done, the disease continued, increasing slowly in all its symptoms from week to week. Soon the hands, also, became affected, so that the little boy could not feed himself. The mind now began to fail. The bright eyes became vacant and expressionless. Instead of the merry light which used to shine in them, there was a blank, idiotic stare. Imagine the grief and anguish of the poor mother! No one but a mother who has been called to pass through a similar trial could know how to sympathize with such a one. Her darling son she saw daily becoming a prey to a strange, incurable malady, with no power even to stay the progress of the terrible disease. But there was still greater grief in store for her. Within a year or two the younger son began to show symptoms of the same character, and in spite of all that was done, rapidly sank into the same helpless state as his brother. As a last resort, the mother took her boys and came a long journey to place her sons under our care. At that time they were both nearly helpless. Neither could walk but a few steps. They reeled and staggered about like drunken men, falling down upon each other and going through the most agonizing contortions in their attempts to work their way from one chair to another and thus about the room. Their heads were no longer erect, but drooped like wilted flowers. On their faces was a blank, imbecile expression, with a few traces of former intelligence still left. The mouth was open, from the drooping of the lower jaw, and the saliva constantly dribbled upon the clothing. Altogether, it was a spectacle which one does not care to meet every day; the impression made was too harrowing to be pleasant even from its interest from a scientific
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