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roducing irritation and inflammation of those organs. Mucus is often formed in large quantities; sometimes much is retained in the bladder. Earthy matter is deposited, which becomes entangled in the mucus, and thus a concretion or stone is produced, occasioning much suffering, and perhaps death. We saw, not long since, a case of this kind. The patient was nearly sixty years of age, and had practiced masturbation from childhood. In consequence of his vice, a chronic irritation of the urethra had been produced, which was followed by enlargement of the prostate, then by chronic irritation of the bladder and the formation of stone. His sufferings were most excruciating whenever he attempted to urinate, which was only accomplished with the greatest difficulty and suffering. One of the unpleasant results of irritation of the lining membrane of the bladder is inability to retain the urine long, which requires frequent urination and often causes incontinence of urine. _Priapism_.--This same morbid sensitiveness may produce priapism, or continuous and painful erection, one of the most "terrible and humiliating conditions," as Dr. Acton says, to which the human body is subject. The horrid desperation of patients suffering under this condition is almost inconceivable. It is, fortunately, rare, in its most severe forms; but hundreds suffer from it to a most painful degree as one of the punishments of transgression of nature's laws; and a most terrible punishment it is. _Piles, Prolapsus of Rectum, etc._--As the result of the straining caused by stricture, piles, prolapsus of the rectum, and fissure of the anus are not infrequently induced, as the following case observed at Charity Hospital, New York, illustrates:-- The patient had a peculiar deformity of the genital organs, _hypospadias_, which prevented sexual intercourse, in consequence of which he gave himself up to the practice of self-abuse. He had become reduced to the most deplorable condition of both mind and body, and presented a most woebegone countenance. In addition to his general ailments, he suffered from extreme prolapsus of the rectum and a most painful anal fissure. His condition was somewhat bettered by skillful surgical treatment. _Extension of Irritation_.--Serious and painful as are the affections already noticed, those which arise from the extension of the congestion and irritation of the urethra to those other organs most intimately connected wi
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