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: "_First generation_: Immorality, depravity, excess in the use of alcoholic liquors, moral debasement. _Second generation_: Hereditary drunkenness, paroxysms of mania, general paralysis. _Third generation_: Sobriety, hypochondria, melancholy, systematic ideas of being persecuted, homicidal tendencies. _Fourth generation_: Intelligence slightly developed, first accessions of mania at sixteen years of age, stupidity, subsequent idiocy and probable extinction of family." Dr. T.D. Crothers, in an analysis of the hundred cases of inebriety received at the New York Inebriate Asylum, gives this result: "Inebriety inherited direct from parents was traced in twenty-one cases. In eleven of these the father drank alone, in six instances the mother drank, and in four cases both parents drank. "In thirty-three cases inebriety was traced to ancestors more remote, as grandfather, grandmother, etc., etc., the collateral branches exhibiting both inebriety and insanity. In some instances a whole generation had been passed over, and the disorders of the grandparents appeared again. "In twenty cases various neurosal disorders had been prominent in the family and its branches, of which neuralgia, chorea, hysteria, eccentricity, mania, epilepsy and inebriety, were most common. "In some cases, a wonderful periodicity in the outbreak of these disorders was manifested. "For instance, in one family, for two generations, inebriety appeared in seven out of twelve members, after they had passed forty, and ended fatally within ten years. In another, hysteria, chorea, epilepsy and mania, with drunkenness, came on soon after puberty, and seemed to deflect to other disorders, or exhaust itself before middle life. This occurred in eight out of fourteen, extending over two generations. In another instance, the descendants of three generations, and many of the collateral branches, developed inebriety, mental eccentricities, with other disorders bordering on mania, at about thirty-five years of age. In some cases this lasted only a few years, in others a lifetime." And here let us say that in this matter of an inherited appetite there is a difference of views with some who believe that appetite is never transmitted but always acquired. This difference of view is more apparent than real. It is not the drunkard's appetite that is transmitted, but the bias or proclivity which renders the subject of such an inherited tendency more susceptible to
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