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ows, they grow larger and more firm. The nipple becomes more prominent, and the circle around its base altered in color and structure, constituting what is called the areola, and as pregnancy advances milk is secreted. THE PERIOD OF GESTATION, at which these changes may occur, varies much in different females. Sometimes, with the exception of the secretion of the milk, they are recognized very soon after conception; in other instances, particularly in females of a weakly and delicate constitution, they are hardly perceptible until pregnancy is far advanced or even drawing toward its termination. The changes in the form and size of the breasts may be the result of causes unconnected with pregnancy. They may enlarge in consequence of marriage, from the individual becoming stout and fat or from accidental suppression of the monthly flow. The changes which take place in the nipple, and around its base, are of the utmost value as an evidence of pregnancy. ABOUT THE SIXTH OR SEVENTH WEEK after conception has taken place, if the nipple be examined it will be found becoming turgid and prominent, and a circle forming around its base, of a color deeper in its shade than rose or flesh color, slightly tinged with a yellowish or brownish hue, and here and there upon its surface will be seen little prominent points from about ten to twenty in number. In the progress of the next six or seven weeks these changes are fully developed, the nipple becoming more prominent and turgid than ever, the circle around it of larger dimensions, the skin being soft, bedewed with a slight degree of moisture, frequently staining the linen in contact with it; the little prominences of larger size, and the color of the whole very much deepened. Calculations of the DURATION OF PREGNANCY, founded upon what has been observed to occur after casual intercourse, or perhaps a single act, in individuals who can have no motive to tell us what is false, are likely to be correct. The conclusion drawn from these is, that labor usually, but not invariably, comes on about 280 days after conception, a mature child being sometimes born before the expiration of the forty weeks, and at other times not until that time has been exceeded by several days. A case is on record where the pregnancy lasted 287 days. In this case the labor did not take place until that period had elapsed fr
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