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arthquake, the whole appears to have been rebuilt by Xenophon, the physician and poisoner of the emperor Claudius. The final destruction was brought about by the earthquake of A.D. 554. Among other things the precinct contains a fountain of water with medicinal properties. It is doubtful whether this water is brought from Burinna, the famous fountain of Hippocrates in the mountain above. _History._--Cos was a Dorian colony with a large contingent of settlers from Epidaurus who took with them their Asclepius cult and made their new home famous for its sanatoria. The other chief sources of the island's wealth lay in its wines, and in later days, in its silk manufacture. Its early history is obscure. During the Persian wars it was ruled by tyrants, but as a rule it seems to have been under an oligarchic government. In the 5th century it joined the Delian League, and after the revolt of Rhodes served as the chief Athenian station in the south-eastern Aegean (411-407). In 366 a democracy was instituted. After helping, in the Social War (357-355), to weaken Athenian power it fell for a few years to the Carian prince Maussollus. In the Hellenistic age Cos attained the zenith of its prosperity. Its alliance was valued by the kings of Egypt, who used it as an outpost for their navy to watch the Aegean. As a seat ef learning it rose to be a kind of provincial branch of the museum of Alexandria, and became a favourite resort for the education of the princes of the Ptolemaic dynasty; among its most famous sons were the physician Hippocrates, the painter Apelles, the poets Philetas and, perhaps, Theocritus (q.v.). Following the lead of its great neighbour, Rhodes, Cos generally displayed a friendly attitude towards the Romans; in A.D. 53 it was made a free city. In A.D. 1315 it was occupied by the Knights of St John; in 1523 it passed under Ottoman sway. Except for occasional incursions by corsairs and some severe earthquakes the island has rarely had its peace disturbed. AUTHORITIES.--L. Ross, _Reisen nach Kos, &c._ (Halle, 1852), pp. 11-29, and _Reisen auf den griechischen Inseln_ (Stuttgart, 1840-1845), ii. 86 ff.; O. Rayet, _Memoire sur l'ile de Cos_ (Paris, 1876); M. Dubois, _De Co Insula_ (Paris and Nancy, 1884); W. Paton and E. Hicks, _The Inscriptions of Cos_ (Oxford, 1891); B. V. Head, _Historia Numorum_ (Oxford, 1887), pp. 535-537; _Archaol. Anzeiger_, 1905, i.; for coins see also NUMISMATICS: Greek, S "Ca
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